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Administration of recombinant interferon gamma to cancer patients enhances monocyte secretion of hydrogen peroxide.

Recombinant interferon gamma (rIFN-gamma) activates macrophage antimicrobial and antitumor functions and related metabolic processes, including secretion of reactive oxygen intermediates in mice and in cultured mouse and human macrophages. To look for similar actions in man, we monitored the H2O2 se...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Nathan, C F, Horowitz, C R, de la Harpe, J, Vadhan-Raj, S, Sherwin, S A, Oettgen, H F, Krown, S E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391501/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3936042/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8686
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