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Administration of recombinant interferon gamma to cancer patients enhances monocyte secretion of hydrogen peroxide.

Recombinant interferon gamma (rIFN-gamma) activates macrophage antimicrobial and antitumor functions and related metabolic processes, including secretion of reactive oxygen intermediates in mice and in cultured mouse and human macrophages. To look for similar actions in man, we monitored the H2O2 se...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Nathan, C F, Horowitz, C R, de la Harpe, J, Vadhan-Raj, S, Sherwin, S A, Oettgen, H F, Krown, S E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391501/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3936042/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8686
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