Pristane-Induced Arthritis Loci Interact with the Slc11a1 Gene to Determine Susceptibility in Mice Selected for High Inflammation

AIRmax (maximal inflammation) and AIRmin (minimal inflammation) mice show distinct susceptibilities to pristane-induced arthritis (PIA). The Slc11a1 gene, which regulates macrophage and neutrophil activity, is involved in this infirmity. AIRmax(SS) mice homozygous for the non-functional Slc11a1 S (g...

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Main Authors: De Franco, Marcelo, Peters, Luciana C., Correa, Mara A., Galvan, Antonella, Canhamero, Tatiane, Borrego, Andrea, Jensen, José R., Gonçalves, Jussara, Cabrera, Wafa H. K., Starobinas, Nancy, Ribeiro, Orlando G., Dragani, Tommaso, Ibañez, Olga M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914970/
https://ncbi.nlm.nih.gov/pubmed/24505471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088302
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