High-Content, High-Throughput Screening for the Identification of Cytotoxic Compounds Based on Cell Morphology and Cell Proliferation Markers

Toxicity is a major cause of failure in drug discovery and development, and whilst robust toxicological testing occurs, efficiency could be improved if compounds with cytotoxic characteristics were identified during primary compound screening. The use of high-content imaging in primary screening is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Martin, Heather L., Adams, Matthew, Higgins, Julie, Bond, Jacquelyn, Morrison, Ewan E., Bell, Sandra M., Warriner, Stuart, Nelson, Adam, Tomlinson, Darren C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914966/
https://ncbi.nlm.nih.gov/pubmed/24505478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088338
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