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Induction and upregulation by interleukin 2 of high-affinity interleukin 2 receptors on thymocytes and T cells.

We show that purified recombinant interleukin 2 (rIL-2) alone induces the expression of high- and low-affinity interleukin 2 (IL-2) receptors in vitro on human T cells and thymocytes that have not been activated previously by lectins or other inducing agents. IL-2 receptors are expressed after 24 hr...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Reem, G H, Yeh, N H, Urdal, D L, Kilian, P L, Farrar, J J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391496/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3936041/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8663
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