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An in vivo assay for elucidating the importance of cytochromes P450 for the ability of a wild mammalian herbivore (Neotoma lepida) to consume toxic plants

An in vivo assay using the cytochrome P450 (P450) suicide inhibitor 1-aminobenzotriazole (ABT) and 24 hour food intake was developed to determine the relative importance of P450s in two populations of Neotoma lepida with respect to biotransformation of plant secondary compounds (PSCs) in the animals...

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Main Authors: Skopec, Michele M., Malenke, Jael, Halpert, James R., Dearing, M. Denise
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914770/
https://ncbi.nlm.nih.gov/pubmed/23995490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/672212
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