Mutations that impair a posttranscriptional step in expression of HLA-A and -B antigens.

Mutations can interfere with posttranscriptional expression of the HLA-A and -B genes. B-lymphoblastoid cells that contain one copy of the major histocompatibility complex (MHC) were subjected to mutagenesis and immunoselection for MHC antigen-loss mutants. Some mutations partially reduced surface e...

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Bibliographic Details
Main Authors: DeMars, R, Rudersdorf, R, Chang, C, Petersen, J, Strandtmann, J, Korn, N, Sidwell, B, Orr, H T
Format: Artigo
Language:Inglês
Published: 1985
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC391467/
https://ncbi.nlm.nih.gov/pubmed/3906658
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