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Efficient synthesis of cis-2,6-di-(2- quinolylpiperidine)
An efficient synthesis of cis-2,6-di-(2-quinolylpiperidine) has been developed. The key steps involve Wittig reaction of N-Cbz-protected cis-piperidine-2,6-dicarboxaldehyde (3) with 2-(triphenylphosphinyl- methyl)quinoline bromide (4) and sequential removal of the N-Cbz group and double bond reducti...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914661/ https://ncbi.nlm.nih.gov/pubmed/24511163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.07.067 |
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