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Identification of a polymorphic variant associated with HLA-DQw3 and characterized by specific restriction sites within the DQ beta-chain gene.

Restriction endonuclease digestion of genomic DNA from 24 lymphoblastoid cell lines homozygous for the HLA class II specificity DQw3, followed by hybridization with a DQ beta-chain cDNA probe, identified a genomic polymorphism with variable BamHI and HindIII recognition sites. This restriction fragm...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kim, S J, Holbeck, S L, Nisperos, B, Hansen, J A, Maeda, H, Nepom, G T
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391458/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2999795/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.8139
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