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Customizing the Therapeutic Response of Signaling Networks to Promote Antitumor Responses by Drug Combinations
Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention. This resistance is one of the key determinants of efficacy in targeted anti-cancer drug therapy. Although poorly understoo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914444/ https://ncbi.nlm.nih.gov/pubmed/24551596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00013 |
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