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Customizing the Therapeutic Response of Signaling Networks to Promote Antitumor Responses by Drug Combinations

Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention. This resistance is one of the key determinants of efficacy in targeted anti-cancer drug therapy. Although poorly understoo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Goltsov, Alexey, Langdon, Simon P., Goltsov, Gregory, Harrison, David J., Bown, James
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914444/
https://ncbi.nlm.nih.gov/pubmed/24551596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00013
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