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Rottlerin-induced autophagy leads to the apoptosis in breast cancer stem cells: molecular mechanisms

BACKGROUND: Autophagy is an indispensable lysosomal self-digestion process involved in the degradation of aggregated proteins and damaged organelles. Autophagy is associated with the several pathological processes, including cancer. Cancer stem cells (CSCs) play significant roles in cancer initiatio...

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Hlavní autoři: Kumar, Dhruv, Shankar, Sharmila, Srivastava, Rakesh K
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914415/
https://ncbi.nlm.nih.gov/pubmed/24359639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-171
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