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How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis

Understanding the impact of the p53 tumor suppressor pathway on the regulation of genome integrity, cancer development, and cancer treatment has intrigued scientists and clinicians for decades. It appears that the p53 pathway is a central node for nearly all cell stress responses, including: gene ex...

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Detalhes bibliográficos
Main Authors: Elkholi, Rana, Chipuk, Jerry E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914234/
https://ncbi.nlm.nih.gov/pubmed/24323920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300117
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