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Prevention of type I diabetes in nonobese diabetic mice by allogenic bone marrow transplantation.

An animal model [the nonobese diabetic (NOD) mouse] for type I diabetes features a striking infiltration of T cells into the pancreatic islets. This infiltration selectively destroys beta cells. Most of the T cells are Lyt-1+, but some are Lyt-2+,3+. Transfer experiments using parabiosis revealed th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ikehara, S, Ohtsuki, H, Good, R A, Asamoto, H, Nakamura, T, Sekita, K, Muso, E, Tochino, Y, Ida, T, Kuzuya, H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391410/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3906651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.22.7743
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