Synthesis, in vitro aerobic and hypoxic cytotoxicity and radiosensitizing activity of novel metronidazole tethered 5-fluorouracil

BACKGROUND AND THE PURPOSE OF THE STUDY: Several 2, 4-dinitrophenyl and 2,4-dinitrophenylamine tethered 5-FU (5-fluorouracil) compared to their components have shown minimal or no cytotoxicity to HT-29 cell line under aerobic conditions but high cytotoxicity and radiosensitizing effects under hypoxi...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Abdi, Khosrou, Khalaj, Ali, Ostad, Seyed Nasser, Lamei, Navid, Khoshayand, Mohammad Reza
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914007/
https://ncbi.nlm.nih.gov/pubmed/24359860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-21-76
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky