RNA Sequencing Identifies Multiple Fusion Transcripts, Differentially Expressed Genes, and Reduced Expression of Immune Function Genes in BRAF (V600E) Mutant vs BRAF Wild-Type Papillary Thyroid Carcinoma

CONTEXT: The BRAF V600E mutation (BRAF-MUT) confers an aggressive phenotype in papillary thyroid carcinoma, but unidentified additional genomic abnormalities may be required for full phenotypic expression. OBJECTIVE: RNA sequencing (RNA-Seq) was performed to identify genes differentially expressed b...

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Detalhes bibliográficos
Main Authors: Smallridge, Robert C., Chindris, Ana-Maria, Asmann, Yan W., Casler, John D., Serie, Daniel J., Reddi, Honey V., Cradic, Kendall W., Rivera, Michael, Grebe, Stefan K., Necela, Brian M., Eberhardt, Norman L., Carr, Jennifer M., McIver, Bryan, Copland, John A., Aubrey Thompson, E.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
JCEM Online: Advances in Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913813/
https://ncbi.nlm.nih.gov/pubmed/24297791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-2792
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