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Inhibition of the Mg(II).ATP-dependent phosphoprotein phosphatase by the regulatory subunit of cAMP-dependent protein kinase.

We report potent inhibition of the Mg(II).ATP-dependent protein phosphatase, Fc.M, by the regulatory subunit dimer of type II cAMP-dependent protein kinase, RII2. The protein kinase catalytic subunit has no effect on phosphatase activity and is unable to substitute for kinase FA in the kinase FA- an...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jurgensen, S R, Chock, P B, Taylor, S, Vandenheede, J R, Merlevede, W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391373/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2999770/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.22.7565
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