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Passenger Protein Determines Translocation Versus Retention in the Endoplasmic Reticulum for Aromatase Expression
Aromatase protein is overexpressed in the breasts of women affected with cancer. In the endoplasmic reticulum (ER), signal sequence and signal anchors (SAs) facilitate translocation and topology of proteins. To understand the function of type-I SAs (SA-Is), we evaluated translocation of aromatase, w...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3913354/ https://ncbi.nlm.nih.gov/pubmed/24280011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.090431 |
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