Miniature endplate current rise times less than 100 microseconds from improved dual recordings can be modeled with passive acetylcholine diffusion from a synaptic vesicle.

We recorded miniature endplate currents (mEPCs) using simultaneous voltage clamp and extracellular methods, allowing correction for time course measurement errors. We obtained a 20-80% rise time (tr) of approximately 80 micros at 22 degrees C, shorter than any previously reported values, and tr vari...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Stiles, J R, Van Helden, D, Bartol, T M, Salpeter, E E, Salpeter, M M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39132/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8650164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.12.5747
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