Pre-hospital hypertonic saline resuscitation attenuates the activation and promotes apoptosis of neutrophils in patients with severe traumatic brain injury

BACKGROUND: Activation of polymorphonuclear neutrophils (PMN) is thought to contribute to traumatic brain injury (TBI). Because hypertonic fluids can inhibit PMN activation, we studied whether hypertonic fluid resuscitation can reduce PMN activation in TBI patients. METHODS: Trauma patients with sev...

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Detalhes bibliográficos
Main Authors: Junger, Wolfgang G., Rhind, Shawn G., Rizoli, Sandro B., Cuschieri, Joseph, Baker, Andrew J., Shek, Pang N., Hoyt, David B., Bulger, Eileen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913169/
https://ncbi.nlm.nih.gov/pubmed/24088993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000038
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