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Napyradiomycin Derivatives, Produced by a Marine-Derived Actinomycete, Illustrate Cytotoxicity by Induction of Apoptosis

The microbial production, isolation and structure elucidation of four new napyradiomycin congeners (1–4) is reported. The structures of these compounds, which are new additions to the marine-derived meroterpenoids, were defined by comprehensive spectroscopic analysis and by X-ray crystallography. Us...

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Detalhes bibliográficos
Main Authors: Farnaes, Lauge, Coufal, Nicole G., Kauffman, Christopher A., Rheingold, Arnold L., DiPasquale, Antonio G., Jensen, Paul R., Fenical, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913167/
https://ncbi.nlm.nih.gov/pubmed/24328269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400466j
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