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The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors.

The nude mutation (nu) causes athymia and hairlessness, but the molecular mechanisms by which it acts have not been determined. To address the role of nu in thymogenesis, we investigated whether all or part of the nude thymic epithelium could be rescued by the presence of wild-type cells in nude <--...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Blackburn, C C, Augustine, C L, Li, R, Harvey, R P, Malin, M A, Boyd, R L, Miller, J F, Morahan, G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39131/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8650163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.12.5742
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