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The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors.

The nude mutation (nu) causes athymia and hairlessness, but the molecular mechanisms by which it acts have not been determined. To address the role of nu in thymogenesis, we investigated whether all or part of the nude thymic epithelium could be rescued by the presence of wild-type cells in nude <--...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Blackburn, C C, Augustine, C L, Li, R, Harvey, R P, Malin, M A, Boyd, R L, Miller, J F, Morahan, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39131/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8650163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.12.5742
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