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Interaction between stress and the BDNF Val66Met polymorphism in depression: a systematic review and meta-analysis

BACKGROUND: Major depression is a disabling psychiatric illness with complex origins. Life stress (childhood adversity and recent stressful events) is a robust risk factor for depression. The relationship between life stress and Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) g...

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Detalhes bibliográficos
Main Authors: Hosang, Georgina M, Shiles, Celia, Tansey, Katherine E, McGuffin, Peter, Uher, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912923/
https://ncbi.nlm.nih.gov/pubmed/24433458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-12-7
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