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Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain.

The human X-linked phosphoglycerate kinase (PGK) gene, which is expressed in all somatic cells, was cloned and its structure was determined. The gene is interrupted by 10 introns and spans 23 kilobases. When projected on the three-dimensional structure of the PGK protein molecule, splice junctions a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Michelson, A M, Blake, C C, Evans, S T, Orkin, S H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391290/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2995995/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.20.6965
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