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Leukotriene C4 production by murine mast cells: evidence of a role for extracellular leukotriene A4.

The glutathione-containing leukotriene C4 (LTC4) is a major mediator of smooth muscle contraction and is released by mast cells when antigen interacts with cell-bound IgE. Antigen-stimulated mast cells undergo phospholipase activation. We report a pathway of LTC4 production by mast cells that does n...

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Detalhes bibliográficos
Main Authors: Dahinden, C A, Clancy, R M, Gross, M, Chiller, J M, Hugli, T E
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC391264/
https://ncbi.nlm.nih.gov/pubmed/2995976
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