Pretreatment of liver grafts in vivo by γ-aminobutyric acid receptor regulation reduces cold ischemia/warm reperfusion injury in rat

BACKGROUND: Gamma-aminobutyric acid (GABA) is found throughout the body. The regulation of GABA receptor (GABAR) reduces oxidative stress (OS). Ischemia/reperfusion injury after orthotopic liver transplantation (OLT) causes OS-induced graft damage. The effects of GABAR regulation in donors in vivo w...

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Bibliographic Details
Main Authors: Hori, Tomohide, Gardner, Lindsay B., Hata, Toshiyuki, Chen, Feng, Baine, Ann-Marie T., Uemoto, Shinji, Nguyen, Justin H.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912510/
https://ncbi.nlm.nih.gov/pubmed/23792534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/AOT.883955
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