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Expression of codon optimized genes in microbial systems: current industrial applications and perspectives

The efficient production of functional proteins in heterologous hosts is one of the major bases of modern biotechnology. Unfortunately, many genes are difficult to express outside their original context. Due to their apparent “silent” nature, synonymous codon substitutions have long been thought to...

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Detalhes bibliográficos
Main Authors: Elena, Claudia, Ravasi, Pablo, Castelli, María E., Peirú, Salvador, Menzella, Hugo G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912506/
https://ncbi.nlm.nih.gov/pubmed/24550894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00021
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