Structure Dependent Binding of Arylimidamides to the DNA Minor Groove

Heterocyclic diamidines are strong DNA minor groove binders and have excellent antiparasitic activity. To extend the biological activity of these compounds, a series of arylimidamides (AIAs) analogs, which have better uptake properties in Leishmania and T. cruizi than diamidines, was prepared. The b...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chai, Yun, Munde, Manoj, Kumar, Arvind, Mickelson, Leah, Lin, Sen, Campbell, Nancy H., Banerjee, Moloy, Akay, Senol, Liu, Zongying, Farahat, Abdelbasset A., Nhili, Raja, Depauw, Sabine, David-Cordonnier, Marie-Hélène, Neidle, Stephen, Wilson, W. David, Boykin, David W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912452/
https://ncbi.nlm.nih.gov/pubmed/24323836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300622
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