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An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic disease
Metastasis is the result of stochastic genomic and epigenetic events leading to gene expression profiles that drive tumor dissemination. Here we exploit the principle that metastatic propensity is modified by the genetic background to generate prognostic gene expression signatures that illuminate re...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912413/ https://ncbi.nlm.nih.gov/pubmed/24322557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.166223.113 |
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