Higher Activity of the Inducible Nitric Oxide Synthase Contributes to Very Early Onset Inflammatory Bowel Disease

OBJECTIVES: The NOS2 gene encodes for the inducible nitric oxide synthase (iNOS), responsible for nitric oxide (NO) production, which contributes to antimicrobial and antipathogenic activities. Higher levels of both iNOS and NO-induced damage have been observed in inflammatory bowel disease (IBD) pa...

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Detalhes bibliográficos
Main Authors: Dhillon, Sandeep S, Mastropaolo, Lucas A, Murchie, Ryan, Griffiths, Christopher, Thöni, Cornelia, Elkadri, Abdul, Xu, Wei, Mack, Amanda, Walters, Thomas, Guo, Conghui, Mack, David, Huynh, Hien, Baksh, Shairaz, Silverberg, Mark S, Brumell, John H, Snapper, Scott B, Muise, Aleixo M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Inflammatory Bowel Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912315/
https://ncbi.nlm.nih.gov/pubmed/24430113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2013.17
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