Fatty Acid Synthase Inhibitor C75 Ameliorates Experimental Colitis

Abnormalities of lipid metabolism through overexpression of fatty acid synthase (FASN), which catalyzes the formation of long-chain fatty acids, are associated with the development of inflammatory bowel disease (IBD). C75 is a synthetic α-methylene-γ-butyrolactone compound that inhibits FASN activit...

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Hauptverfasser: Matsuo, Shingo, Yang, Weng-Lang, Aziz, Monowar, Kameoka, Shingo, Wang, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: ScholarOne 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912252/
https://ncbi.nlm.nih.gov/pubmed/24306512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2013.00113
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