Biological significance of carbohydrate chains on monoclonal antibodies.
We have prepared monoclonal hapten-specific mouse IgG2b antibodies depleted of asparagine-linked carbohydrate chains by treating the hybridoma cells with tunicamycin. The carbohydrate-deficient antibodies behaved in an identical manner to the normal antibodies with regard to fine antigen-binding rea...
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| Vydáno v: | Proc Natl Acad Sci U S A |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1983
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391224/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6579549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.21.6632 |
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