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Establishment of HeLa Cell Mutants Deficient in Sphingolipid-Related Genes Using TALENs
Sphingolipids are essential components in eukaryotes and have various cellular functions. Recent developments in genome-editing technologies have facilitated gene disruption in various organisms and cell lines. We here show the disruption of various sphingolipid metabolic genes in human cervical car...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912166/ https://ncbi.nlm.nih.gov/pubmed/24498430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088124 |
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