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AST-120 for the management of progression of chronic kidney disease

Uremic toxins such as indoxyl sulfate contribute to the pathogenesis of chronic kidney disease (CKD) by promoting glomerulosclerosis and interstitial fibrosis with loss of nephrons and vascular damage. AST-120, an orally administered intestinal sorbent, adsorbs indole, a precursor of indoxyl sulfate...

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Detalles Bibliográficos
Main Authors: Schulman, Gerald, Vanholder, Raymond, Niwa, Toshimitsu
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912158/
https://ncbi.nlm.nih.gov/pubmed/24501542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJNRD.S41339
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