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Prevention of Allogeneic Cardiac Graft Rejection by Transfer of Ex Vivo Expanded Antigen-Specific Regulatory T-Cells

The rate of graft survival has dramatically increased using calcineurin inhibitors, however chronic graft rejection and risk of infection are difficult to manage. Induction of allograft-specific regulatory T-cells (Tregs) is considered an ideal way to achieve long-term tolerance for allografts. Howe...

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Главные авторы: Takasato, Fumika, Morita, Rimpei, Schichita, Takashi, Sekiya, Takashi, Morikawa, Yasuhide, Kuroda, Tatsuo, Niimi, Masanori, Yoshimura, Akihiko
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912059/
https://ncbi.nlm.nih.gov/pubmed/24498362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087722
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