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Selective anti-cancer agents as anti-aging drugs

Recent groundbreaking discoveries have revealed that IGF-1, Ras, MEK, AMPK, TSC1/2, FOXO, PI3K, mTOR, S6K, and NFκB are involved in the aging process. This is remarkable because the same signaling molecules, oncoproteins and tumor suppressors, are well-known targets for cancer therapy. Furthermore,...

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Bibliografische gegevens
Hoofdauteur: Blagosklonny, Mikhail V
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912031/
https://ncbi.nlm.nih.gov/pubmed/24345884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27350
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