Synthetic Multivalent Antifungal Peptides Effective against Fungi

Taking advantage of the cluster effect observed in multivalent peptides, this work describes antifungal activity and possible mechanism of action of tetravalent peptide (B4010) which carries 4 copies of the sequence RGRKVVRR through a branched lysine core. B4010 displayed better antifungal propertie...

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Detalhes bibliográficos
Main Authors: Lakshminarayanan, Rajamani, Liu, Shouping, Li, Jianguo, Nandhakumar, Muruganantham, Aung, Thet Tun, Goh, Eunice, Chang, Jamie Ya Ting, Saraswathi, Padhmanaban, Tang, Charles, Safie, Siti Radiah Binte, Lin, Lim Yih, Riezman, Howard, Lei, Zhou, Verma, Chandra S., Beuerman, Roger W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912015/
https://ncbi.nlm.nih.gov/pubmed/24498363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087730
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