Rate of Somatic Mutation in Immunoglobulin Production by Mouse Myeloma Cells
Cultures of mouse myeloma cells which secrete both heavy (H) and light (L) immunoglobulin chains were cloned in soft agar. Variants that synthesized neither chain, or only light chains, were detected by overlaying the growing colonies with antiserum specific for the individual immunoglobulin chains....
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1971
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5276293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.1.219 |
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