Glucokinase Regulatory Protein Gene Polymorphism Affects Liver Fibrosis in Non-Alcoholic Fatty Liver Disease

BACKGROUND AND AIMS: Variant in glucokinase regulatory protein (GCKR), associated with lipid and glucose traits, has been suggested to affect fatty liver infiltration. We aimed to assess whether GCKR rs780094 C→T SNP influences the expression of steatosis, lobular inflammation and fibrosis in NAFLD...

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Detalhes bibliográficos
Main Authors: Petta, Salvatore, Miele, Luca, Bugianesi, Elisabetta, Cammà, Calogero, Rosso, Chiara, Boccia, Stefania, Cabibi, Daniela, Di Marco, Vito, Grimaudo, Stefania, Grieco, Antonio, Pipitone, Rosaria Maria, Marchesini, Giulio, Craxì, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911959/
https://ncbi.nlm.nih.gov/pubmed/24498332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087523
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