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Kinetic Analysis Demonstrates a Requirement for the Rat1 Exonuclease in Cotranscriptional Pre-rRNA Cleavage

During yeast ribosome synthesis, three early cleavages generate the 20S precursor to the 18S rRNA component of the 40S subunits. These cleavages can occur either on the nascent transcript (nascent transcript cleavage; NTC) or on the 35S pre-rRNA that has been fully transcribed and released from the...

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Detalhes bibliográficos
Main Authors: Axt, Konstantin, French, Sarah L., Beyer, Ann L., Tollervey, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911906/
https://ncbi.nlm.nih.gov/pubmed/24498264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085703
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