Immunofluorescent Evidence for Cellular Control of Synthesis of Variable Regions of Light and Heavy Chains of Immunoglobulins G and M by the Same Gene

Two distinct paraproteins (IgG(2)-K and IgM-K) from one patient shared identical light chains and significant portions of the variable regions of the heavy chains. Idiotypic determinants on the IgG and IgM molecules were shared. Earlier studies, using class-specific antisera, showed that these parap...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Levin, A. S., Fudenberg, H. H., Hopper, J. E., Wilson, S. K., Nisonoff, A.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1971
Subjects:	Biological Sciences: Immunology
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391188/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5276287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.1.169
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