Versatile Roles of CspA Orthologs in Complement Inactivation of Serum-Resistant Lyme Disease Spirochetes

CspA of the Lyme disease spirochete Borrelia burgdorferi represents a key molecule in immune evasion, protecting borrelial cells from complement-mediated killing. As previous studies focused almost exclusively on CspA of B. burgdorferi, here we investigate the different binding capacities of CspA or...

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Autores principales: Hammerschmidt, Claudia, Koenigs, Arno, Siegel, Corinna, Hallström, Teresia, Skerka, Christine, Wallich, Reinhard, Zipfel, Peter F., Kraiczy, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911871/
https://ncbi.nlm.nih.gov/pubmed/24191298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01094-13
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