Bacterially Expressed Full-Length Recombinant Plasmodium falciparum RH5 Protein Binds Erythrocytes and Elicits Potent Strain-Transcending Parasite-Neutralizing Antibodies

Plasmodium falciparum reticulocyte binding-like homologous protein 5 (PfRH5) is an essential merozoite ligand that binds with its erythrocyte receptor, basigin. PfRH5 is an attractive malaria vaccine candidate, as it is expressed by a wide number of P. falciparum strains, cannot be genetically disru...

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Detalhes bibliográficos
Main Authors: Reddy, K. Sony, Pandey, Alok K., Singh, Hina, Sahar, Tajali, Emmanuel, Amlabu, Chitnis, Chetan E., Chauhan, Virander S., Gaur, Deepak
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911863/
https://ncbi.nlm.nih.gov/pubmed/24126527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00970-13
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