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Exoenzyme S ADP-Ribosylates Rab5 Effector Sites To Uncouple Intracellular Trafficking

Pseudomonas aeruginosa exoenzyme S (ExoS) ADP-ribosylates multiple eukaryotic targets to promote cytopathology and bacterial colonization. ADP-ribosylation of the small GTPase Rab5 has previously been shown to block fluid-phase endocytosis and trafficking of plasma membrane receptors to the early en...

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Détails bibliographiques
Auteurs principaux: Simon, Nathan C., Barbieri, Joseph T.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911848/
https://ncbi.nlm.nih.gov/pubmed/24101692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01059-13
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