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Simulation study of the structure and phase behavior of ceramide bilayers and the role of lipid head group chemistry

Ceramides are known to be a key component of the stratum corneum, the outermost protective layer of the skin that controls barrier function. In this work, molecular dynamics simulations are used to examine the behavior of ceramide bilayers, focusing on non-hydroxy sphingosine (NS) and non-hydroxy ph...

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Autores principales: Guo, Shan, Moore, Timothy C., Iacovella, Christopher R., Strickland, L. Anderson, McCabe, Clare
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911788/
https://ncbi.nlm.nih.gov/pubmed/24501589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct400431e
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