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Simulation study of the structure and phase behavior of ceramide bilayers and the role of lipid head group chemistry

Ceramides are known to be a key component of the stratum corneum, the outermost protective layer of the skin that controls barrier function. In this work, molecular dynamics simulations are used to examine the behavior of ceramide bilayers, focusing on non-hydroxy sphingosine (NS) and non-hydroxy ph...

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Hlavní autoři: Guo, Shan, Moore, Timothy C., Iacovella, Christopher R., Strickland, L. Anderson, McCabe, Clare
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911788/
https://ncbi.nlm.nih.gov/pubmed/24501589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct400431e
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