Conditional deletion of cardiomyocyte peroxisome proliferator-activated receptor-γ enhances myocardial ischemia-reperfusion injury in mice

The nuclear transcription factor peroxisome proliferator-activated receptor-γ (PPARγ) is a key regulator of the inflammatory response to an array of biologic insults. We have previously demonstrated that PPARγ ligands reduce myocardial ischemia-reperfusion injury in rodents. In the current study, we...

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Hauptverfasser: Hobson, Michael J., Hake, Paul W., O’Connor, Michael, Schulte, Christine, Moore, Victoria, James, Jeanne M., Piraino, Giovanna, Zingarelli, Basilia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911778/
https://ncbi.nlm.nih.gov/pubmed/24089001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000051
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