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A Novel Cytotoxic Sequence Contributes to Influenza A Viral Protein PB1-F2 Pathogenicity and Predisposition to Secondary Bacterial Infection

Enhancement of cell death is a distinguishing feature of H1N1 influenza virus A/Puerto Rico/8/34 protein PB1-F2. Comparing the sequences (amino acids [aa] 61 to 87 using PB1-F2 amino acid numbering) of the PB1-F2-derived C-terminal peptides from influenza A viruses inducing high or low levels of cel...

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Autori principali: Alymova, Irina V., Samarasinghe, Amali, Vogel, Peter, Green, Amanda M., Weinlich, Ricardo, McCullers, Jonathan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911746/
https://ncbi.nlm.nih.gov/pubmed/24173220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01373-13
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