Effects of Alpha Interferon Treatment on Intrinsic Anti-HIV-1 Immunity In Vivo

Alpha interferon (IFN-α) suppresses human immunodeficiency virus type 1 (HIV-1) replication in vitro by inducing cell-intrinsic retroviral restriction mechanisms. We investigated the effects of IFN-α/ribavirin (IFN-α/riba) treatment on 34 anti-HIV-1 restriction factors in vivo. Expression of several...

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Autori principali: Abdel-Mohsen, Mohamed, Deng, Xutao, Liegler, Teri, Guatelli, John C., Salama, Mohamed S., Ghanem, Hussam El-din A., Rauch, Andri, Ledergerber, Bruno, Deeks, Steven G., Günthard, Huldrych F., Wong, Joseph K., Pillai, Satish K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911728/
https://ncbi.nlm.nih.gov/pubmed/24155399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02687-13
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