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Immunosuppression Facilitates the Reactivation of Latent Papillomavirus Infections

At mucosal sites, papillomavirus genomes can persist in the epithelial basal layer following immune-mediated regression. Subsequent T-cell depletion stimulates a 3- to 5-log increase in the viral copy number, to levels associated with productive infection. Reappearance of microlesions was rare withi...

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Autori principali: Maglennon, G. A., McIntosh, P. B., Doorbar, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911712/
https://ncbi.nlm.nih.gov/pubmed/24173230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02589-13
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