Increased Sequence Coverage through Combined Targeting of Variant and Conserved Epitopes Correlates with Control of HIV Replication

A major challenge in the development of an HIV vaccine is that of contending with the extensive sequence variability found in circulating viruses. Induction of HIV-specific T-cell responses targeting conserved regions and induction of HIV-specific T-cell responses recognizing a high number of epitop...

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Hlavní autoři: Sunshine, Justine, Kim, Moon, Carlson, Jonathan M., Heckerman, David, Czartoski, Julie, Migueles, Stephen A., Maenza, Janine, McElrath, M. Juliana, Mullins, James I., Frahm, Nicole
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911649/
https://ncbi.nlm.nih.gov/pubmed/24227851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02361-13
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