A Targeted Mutation within the Feline Leukemia Virus (FeLV) Envelope Protein Immunosuppressive Domain To Improve a Canarypox Virus-Vectored FeLV Vaccine

We previously delineated a highly conserved immunosuppressive (IS) domain within murine and primate retroviral envelope proteins that is critical for virus propagation in vivo. The envelope-mediated immunosuppression was assessed by the ability of the proteins, when expressed by allogeneic tumor cel...

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Detalhes bibliográficos
Main Authors: Schlecht-Louf, Géraldine, Mangeney, Marianne, El-Garch, Hanane, Lacombe, Valérie, Poulet, Hervé, Heidmann, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911645/
https://ncbi.nlm.nih.gov/pubmed/24198407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02234-13
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