Novel Neuroprotective GSK-3β Inhibitor Restricts Tat-Mediated HIV-1 Replication

The implementation of new antiretroviral therapies targeting transcription of early viral proteins in postintegrated HIV-1 can aid in overcoming current therapy limitations. Using high-throughput screening assays, we have previously described a novel Tat-dependent HIV-1 transcriptional inhibitor nam...

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Detalhes bibliográficos
Main Authors: Guendel, Irene, Iordanskiy, Sergey, Van Duyne, Rachel, Kehn-Hall, Kylene, Saifuddin, Mohammed, Das, Ravi, Jaworski, Elizabeth, Sampey, Gavin C., Senina, Svetlana, Shultz, Leonard, Narayanan, Aarthi, Chen, Hao, Lepene, Benjamin, Zeng, Chen, Kashanchi, Fatah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911635/
https://ncbi.nlm.nih.gov/pubmed/24227837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01940-13
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